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Interestingly, elevated plasma serine levels and abnormal SHMT1/2 activity were first reported in patients with severe or atypical psychoses in 1984 [137]

The substance Rey-Pailhade named has been continuously studied ever since

This study demonstrated that PSSI 90 and PSSI 100 results were maintained until week 60 in patients initially treated with ixekizumab 2-week dosing who were switched to 4-week dosing schedules (79.1% and 75.9%) as well as patients continued on a ixekizumab 4-week dosing schedule (76.2% and 73.6%) [45]

Carnitene should be administered during pregnancy if the benefit to the mother outweighs the potential risks to the fetus